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GLP-1 is an abbreviation for Glucagon-Like Peptide-1 receptor agonist, which is a class of medications commonly used to treat diabetes and to assist with weight loss in patients with or without diabetes

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According to a 2024 report by Grand View Research, the global microneedle market is projected to reach $13.8 billion by 2030 , growing at a CAGR of 16.7% from 2024 to 2030

"Neuroprotective and anti-apoptotic effects of liraglutide on SH-SY5Y cells exposed to methylglyoxal stress"

The risk of gastrointestinal adverse events is increased with GLP-1RA therapy but these effects tend to be mild-to-moderate and transient, and are not the reason for observed weight loss

The result suggests that sympathetic nervous system activation by GLP-1RA is due to direct activation of AP without bloodbrain barrier or indirect activation of NTS via vagal afferent nerves and AP