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Its regulatory network encompasses multiple layers, including post-translational modification, transcriptional regulation and crosstalk with signaling pathways, with marked heterogeneity in regulatory patterns across distinct cancer types

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This pathway is tightly regulated by enzymes such as ornithine aminotransferase (OAT) and pyrroline-5-carboxylate reductase (PYCR), which control proline production and, consequently, the rate of collagen deposition [13,14,15,16]

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Some products make your skin worse before the get better like retinol, which can make your skin dry before it gets better