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The guayusa leaves found give indications of its high value at the time, since the species does not report a presence near the area where they were found, so it is intuited that it was used as a tradable medicine or as an energy source for long trips due to the stimulating effect of the alkaloids it contains [2,27,41]

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In a controlled study, healthy adults who took 16 grams per day of oligofructose for two weeks showed increased colonic fermentation, higher plasma GLP-1 and PYY, lower post-meal glucose, reduced hunger ratings, and a measurable drop in total energy intake

In: Grumezescu AM, editor