The use of AUC in protein studies has undergone two major phases of popularity: a period of initial growth between the 1950s and 1970s (caused by the appearance of commercially available ultracentrifuges), and a resurgence period in the 1990s fueled by significant technological advances including computerized data acquisition, rotor speed, and temperature regulation
But how do you measure them and what can you do with them
Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis
However, existing NADPH sensors face major limitations, including sensitivity to pH, lack of responsiveness to NADP + , signal-to-noise ratio, and compatibility with alternative measurement techniques like FLIM
J Clin Pharmacol 2014
Wang X, Ye XL, Liu R, Chen HL, Bai H, Liang X, et al