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As GSH patrols the cellular environment and puts out oxidative free radical fires, it becomes oxidized and inactive, thus turning into GSSG
Finally, SY could reverse any injury caused to the intestinal barrier after exposure to OTA by acting on the TLR4/MYD88 pathway to prevent NF-B expression while increasing that of the tight junction-related genes ZO-1, Occludin , and Claudin-1 (135)
(1) Heavy metals metabolism and subsequent excretion from the body depends on the presence of antioxidants (glutathione, ascorbate, etc.), which are associated with the quenching of free radicals that often disrupt the activity of critical detoxification enzymes including catalase, peroxidase, and superoxide dismutase (among others)
Biol Forum Int J 14:8490 Kundu V, Iqbal A, Kundagrami S (2025) Emergence of Macrophomina tecta as a causal agent of charcoal rot in sesame: a first global record supported by morphological, pathogenic, and multilocus sequence analysis
