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The fourth step (for refractory/multi-joint OA) is integrate medical nutrition therapy (MNT) based on the previous steps, combined with high-dose -3 PUFAs (EPA + DHA 3 g/day) for enhanced anti-inflammation

Multi-concentration reference: why your vial label matters A patient prescribed 0.9 mg who applies a 2.5 mg/mL table to a 5 mg/mL vial would draw 36 units instead of 18 delivering 1.8 mg, double the intended dose

These are usually mild and transient

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It is important to note that these studies were conducted under strict medical supervision