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The GLP1R/GIPR dual agonist NNC 00902746 (Novo Nordisk) significantly improved hemoglobin A1c (A1c) in T2DM (a reduction of 0.96% vs placebo) over a 12-week period, accompanied by a reduction in body weight

Autoclave: Autoclave Autoclave is used to remove unwanted particles, pyrogens or endotoxins from final preparation of sterile product

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The colonic sections with 4 m thickness were deparaffinized followed by immersion in H 2 O 2 to stop the activity of endogenous peroxidase

Moreover, reduced cerebral vascularization observed in T2DM leads to chronic hypoxia, which is implicated in the progression of AD