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Key clinical factors associated with elevated PSE risk include: Stroke severity (e.g., NIHSS score) Cortical involvement (especially frontal, temporal, or parietal lobes) Lesions in the anterior circulation Large lesion size Hemorrhagic stroke Cerebral vein or sinus thrombosis Cardioembolic stroke subtype Occurrence of early poststroke seizures Several prognostic models have been developed to quantify individual PSE risk