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Yet, despite its relevance, the relationship of betaine and choline to homocysteine metabolism has been only lightly investigated in humans, essentially because the choline content of foods could not be accurately measured until fairly recently

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Circulation 117:23402350 Li Y, Duffy KB, Ottinger MA et al (2010) GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimers disease

CRISPR/Cas9 directed to the Ube3a antisense transcript improves Angelman syndrome phenotype in mice