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Gibco) and 1% Pen-Strep (Gibco) in a humidified atmosphere with 5% CO 2 at 37C

The understanding of the etiology of migraine is incomplete

In the context of erythrocyte death, several enzymatic activities have been described to be involved in sphingomyelin breakdown: (i) cigarette smoke extracts (CSEs) elicit neutral SMase activity-dependent erythrocytic ceramide formation [130]

Transport of brain-derived neurotrophic factor across the bloodbrain barrier

Hepcidin, a liver-derived peptide hormone, also exerts a crucial negative feedback role in cerebral iron regulation